||Rating:Â 7,7/10 (128,944 votes)
Stars:Â Ellen Pompeo, Justin Chambers, Chandra Wilson,Â James Pickens Jr,Â Patrick Dempsey
Runtime: 60 min
Genre:Â Drama, Romance
Released:Â MarchÂ 27,Â 2005
|Pilot:Â Derek gets in on the idea of making a map of the human brain. It has lots of connections with a specific pattern that determines everything about us. Heâ€™s been doing tests on an enthusiastic quadriplegic named Mickey. The project was actually initiated by Callie, who doesnâ€™t believe she has time to continue with it. In reality, itâ€™s because she first started the project for Arizona. In other news, Meredith is desperately trying to come up with a subject for a research grant. She doesnâ€™t necessarily want to pursue an interesting portal vein study because itâ€™s something her mother started. She eventually realizes thatâ€™s no reason to not do something great. Derek accidentally brings a coffee mug from home to work. Shane is asked to put it with the rest of his belongings. He gets a first class case of the guilts when he sees Heatherâ€™s second-year lab coat in the locker next to his. To make matters worse, Jo accidently swipes the coffee mug Shane was supposed to care for. She ends up smashing it. Shane tries his best to glue it back together. Speaking of glue, Derek mentions that the adhesive product is sometimes used to cut off tumors to the brain. But trying this on Mickey, who has a mass, is too risky. Mickey wants Derek to take out his tumor so they can continue doing tests on his brain. Heâ€™s adamant about doing this no matter what the risk. Callie learns why. Mickey caused a car accident that killed two teenage girls. He wants to make up for that. Derek operates on Mickey, but things go south. The patient dies on the table. Itâ€™s sad, but it was Mickeyâ€™s call. He may be gone, but they can still study his brain to help others. Callie lets Derek know that sheâ€™s back on board with their project.